Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy
By Dieter Marm, Norbert Fusenig

Product Description:

Tumor angiogenesis is one of the most prominent mechanisms driving tumor development and progression. In the past 30 years some of the most important signaling pathways linking specific angiogenic activities of tumor cells to fatal reactions of the patient s vascular system have been elucidated. Crucial targets for therapeutic intervention have been identified and validated.
Based on these achievements targeted drug development programs have been implemented to interfere with tumor angiogenesis as an attractive strategy in cancer treatment. The first targeted anti-angiogenic drugs have been approved for a variety of solid metastasizing cancers.

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